Client Information from Zoetis for Beransa Injection

Please review the following information with your veterinarian each time your dog receives Beransa®. This information provides a summary and does not take the place of instructions from your veterinarian.

For additional information on Beransa, including administration, precautions & side-effects, please refer to the product label.

What is Beransa?

Your veterinarian has administered Beransa to your dog to manage their arthritis pain. Arthritis is a chronic and progressive joint disease, causing pain and discomfort for your dog.

Beransa contains bedinvetmab, a monoclonal antibody targeting a protein that stimulates arthritis pain in dogs called Nerve Growth Factor (NGF). Beransa is administered as a monthly injection under the supervision of a veterinarian.

What can I expect from my dog’s treatment with Beransa?

•  While there is no cure for arthritis, each dose of Beransa alleviates arthritis pain for one month.
•  Dogs with arthritis pain often experience a reduced ability to exercise. During initial treatment with Beransa, it is therefore recommended to gradually increase their exercise over the first few months to prevent exercise-related injury.
•  It may take two monthly injections to reach adequate pain reduction. Discontinuation prior to the second injection may not result in maximum pain reduction. If the response to treatment is not as desired after the second injection or subsequent injections, talk to your veterinarian about alternative treatments and please inform Zoetis.

What should I discuss with my veterinarian?

•  Any possible signs of pain you have observed (change in level of activity, limping, stiffness, behaviour changes).
•  The importance of weight control and exercise in the management of arthritis pain.
•  The general health status of your dog.
•  The benefits and risks of using Beransa.
•  All medicines that you are giving your dog or plan to give your dog, including those you can get without a prescription, and nutritional supplements.
• If your dog is breeding, pregnant or lactating.

Dogs should not be given Beransa

•  If your dog is less than 12 months of age.
•  If you have immediate plans to breed your dog or they are pregnant or lactating.
•  If your dog has had an allergic reaction while receiving Beransa (anaphylaxis, itchy skin, facial swelling).
•  If your dog’s current health status is not well understood or has changed recently. In this case, further tests may be recommended prior to starting Beransa.

What possible side effects could occur from the use of Beransa?

The following clinical signs have been reported in dogs receiving Beransa. These signs may indicate your dog is having an adverse reaction to Beransa or alternatively, could indicate that an unrelated medical problem has occurred:

•  Mild swelling or heat at the injection site.
•  Drinking more and/or urinating more.
•  Urinary incontinence.
•  Balance problems or incoordination.
•  Decreased appetite.
•  Lethargy.
•  Very rarely, shock, facial swelling and itchiness (anaphylaxis)
•  Very rarely, autoimmune illnesses affecting the blood.

It is important to contact your veterinarian if you observe any signs of illness in your dog either before they start Beransa, or after they receive Beransa.

Additional diagnostics may be recommended to determine any underlying cause.

Severe reactions such as anaphylaxis require immediate emergency treatment by your veterinarian.

If an adverse reaction is suspected, please inform Zoetis on 1800 814 883 or productsupport.au@zoetis.com.